[HTML][HTML] Cell surface CD36 protein in monocyte/macrophage contributes to phagocytosis during the resolution phase of ischemic stroke in mice
Infiltrating monocyte-derived macrophages (MM Φ) influence stroke-induced brain injury.
Although the inflammatory nature of MM Φ in acute stroke has been well documented, their
role during the resolution phase of stroke is less clear. With emerging evidence for the
involvement of scavenger receptors in innate immunity, this study addresses an MM Φ CD36
role in mediating phagocytosis during the recovery phase of stroke. Stroke increases CD36
and TSP-1/2 mRNA levels in the ipsilateral hemisphere at acute (3-day (d)) and recovery …
Although the inflammatory nature of MM Φ in acute stroke has been well documented, their
role during the resolution phase of stroke is less clear. With emerging evidence for the
involvement of scavenger receptors in innate immunity, this study addresses an MM Φ CD36
role in mediating phagocytosis during the recovery phase of stroke. Stroke increases CD36
and TSP-1/2 mRNA levels in the ipsilateral hemisphere at acute (3-day (d)) and recovery …
