Secretion of cytokines and growth factors into autosomal dominant polycystic kidney disease liver cyst fluid
MT Nichols, E Gidey, T Matzakos, R Dahl… - Hepatology, 2004 - journals.lww.com
The principal extrarenal manifestation of autosomal dominant polycystic kidney disease
(ADPKD) involves formation of liver cysts derived from intrahepatic bile ducts. Autocrine and
paracrine factors secreted into the cyst would be positioned to modulate the rate of hepatic
cyst growth. The aim of this study was to identify potential growth factors present in human
ADPKD liver cyst fluid. Cytokine array and enzyme-linked immunosorbent assay analysis of
human ADPKD liver cyst fluid detected epithelial neutrophil attractant 78, interleukin (IL)-6 …
(ADPKD) involves formation of liver cysts derived from intrahepatic bile ducts. Autocrine and
paracrine factors secreted into the cyst would be positioned to modulate the rate of hepatic
cyst growth. The aim of this study was to identify potential growth factors present in human
ADPKD liver cyst fluid. Cytokine array and enzyme-linked immunosorbent assay analysis of
human ADPKD liver cyst fluid detected epithelial neutrophil attractant 78, interleukin (IL)-6 …
