[HTML][HTML] Human skin collagen. Presence of type I and type III at all levels of the dermis.

EH Epstein Jr, NH Munderloh - Journal of Biological Chemistry, 1978 - Elsevier
EH Epstein Jr, NH Munderloh
Journal of Biological Chemistry, 1978Elsevier
Human skin was sliced with a dermatome, and the ratio of type I to type III collagens at
various depths was assayed by comparing the quantities of peptides of each derived from
cyanogen bromide digestion of the cut skin. Although immunofluorescent studies have
suggested type III collagen is located predominantly beneath the epidermis and around
appendages, biochemical determination demonstrates the same ratio of type I to type III
collagen at all levels of the dermis even in the absence of cutaneous appendages.
Human skin was sliced with a dermatome, and the ratio of type I to type III collagens at various depths was assayed by comparing the quantities of peptides of each derived from cyanogen bromide digestion of the cut skin. Although immunofluorescent studies have suggested type III collagen is located predominantly beneath the epidermis and around appendages, biochemical determination demonstrates the same ratio of type I to type III collagen at all levels of the dermis even in the absence of cutaneous appendages.
Elsevier